Thursday, May 31, 2012

Genome: Chromosome 9 – Disease

Chapter 9 talks about a gene that determines ABO blood type. The A, B, AB, and O is adopted by Viennese discoverer. Native Americans are most exclusively type O. There are four letters in type A: C, G, C, and G whereas there are another four letters in type B: G, A, A, and C. In type O, which is also the same as type A, the 258th letter G is missing or has been deleted. Type O is a recessive chromosome, which is susceptible to Cholera but resistant to Malaria. Type A, B, and AB are resistant to Cholera but susceptible to malaria. The sickle cell disease is a CFTR gene that’s on chromosome 7 and can cause a dangerous disease in the lungs and intestines. The effect of non-secretors means that they are unable to release the water-soluble form of the blood proteins from ABO into their body fluids.

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